Cryptococcosis or cryptococcal disease is a fungal disease, which in severe cases can be fatal. It is caused by either Cryptococcus neoformans or Cryptococcus gattii. Cryptococcosis is said to be acquired by inhaling contagious propagule from surroundings. Even though the accurate character of the contagious propagule is not known, the primary theory is the basidiospore produced in the course of sexual or asexual reproduction is the cause. Cryptococcosis disease symptoms include fatigue, fever, headache, blurred vision, dry cough, and confusion. Symptoms onset is often subacute, worsening progressively over more than a few weeks. The two key complications of the disease are meningitis (brain infection) and pulmonary infection or lung infection. The occurrence of cryptococcosis is increasing over the years for various reasons, such as increase in prevalence of AIDS as well as extended use of immunosuppressive drugs. These factors are likely to propel the growth of the overall cryptococcosis treatment market in the near future.
Increasing prevalence of cryptococcosis in Sub-Saharan Africa will drive the overall cryptococcosis treatment market growth
According to CDC, in 2009, there were an estimated 720,000 cases of HIV related cryptococcosis in the Sub-Saharan Africa, which is about three times the prevalence of the disease in all other parts of the world, combined. It is believed that the disease kills more people in this region than tuberculosis. Moreover, CDC also states that cryptococcosis is the fourth most fatal disease in the region. It is estimated to cause about 504,000 deaths per year. The occurrence of cryptococcosis in the region is growing at an alarming rate; hence, the market in this region is expected to grow at a significant rate over the forecast period.
Some of the major companies operating in the global cryptococcosis treatment market are Bristol-Myers Squibb Company, Sigmapharm Laboratories LLC, Janssen Biotech, Inc. (Johnson & Johnson), Novartis AG, Abbott Laboratories, Valeant Pharmaceuticals, Inc., Pfizer, Inc., and Glenmark Pharmaceuticals.